Abstract

Background and Aims : Homozygous familial hypercholesterolemia (HoFH) is a genetic disorder characterized by extremely high levels of circulating low-density lipoprotein cholesterol (LDL-C). Lomitapide is a microsomal transfer protein inhibitor that has demonstrated LDL receptor-independent lipid-lowering efficacy in HoFH patients in long-term clinical trials and real-world studies.

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