Localisation of aminopeptidase activities in the central and peripheral nervous system of Helix aspersa by fluorescence histochemistry

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1. Tissues of Helix aspersa have been examined histologically for the presence of aminopeptidase activity. 2. A variation of the novel fluorescent histochemical method of Back and Gorenstein (1989) was employed using Phe-, Leu- and Arg-4-methoxynaphthylamide substrates. 3. When using Phe- and Leu- derivatives, specific aminopeptidase activity was localised to neuronal axons in both circumoesophageal ganglia and the foot muscle of Helix aspersa. 4. The Arg compound failed to produce staining.