Abstract
Methods We selected 48 patients with moderate to severe rhinitis (12 of them had intermittent asthma) sensitized to Der p without prior treatment with allergen specific immunotherapy. The protocol was approved by the ethics committee. All participants signed informed consent. Determination of total IgE and specific IgE for Der p1 (D1) and Der p2 (D2) were performed in serum and nasal lavage, using ImmunoCAP method. Non parametric tests were used in the statistical analysis.
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