Abstract
Abstract Background: Although systemic antibiotic therapy is recommended for the prevention and treatment of infection, the use of local antibiotic(s) in the setting of osteomyelitis is well established. Treatment consists of debridement and placement of antibiotics that have been added to bone cement. Hand osteomyelitis will fail periodically after treatment with systemic antibiotics. Debridement is difficult because the fine architecture of the hand limits excessive debridement that might be used in other locations. In the current study, we injected antibiotics directly into the infected bone and soft tissue and had a good result. Case Presentation: A 65-year-old man had a traumatic amputation and replantation of his right hand. He lost the majority of the skin coverage of the dorsum of the amputated hand. During treatment, his residual extensor tendons and bones had severe methicillin-resistant coagulase-negative staphylococcal (MRCNS) infection. Daily drainage and systemic antibiotics for five months ...
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