Abstract
Background: Peripheral arterial disease may be complicated by tissue ischemia and subsequent gangrene. When tissue gangrene is accompanied by septic shock in a patient with comorbid medical conditions and compromised physiology, emergency operation may trigger cardiac complications of non-cardiac surgery. Such patients benefit from resuscitation and cardiac optimization prior to operative intervention. Conclusion: Cryoamputation provides a non-surgical alternative to immediate amputation, arrests bacterial growth, has no known resistance induction, achieves anesthesia, and excludes ischemic tissue and its metabolic byproducts from the circulation. This allows patient resuscitation, metabolic abnormality correction, and cardiac performance optimization prior to definitive operation.
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