Abstract

Living Kidney Transplant: The Influence of Intra-Operative Hemodynamics on Delayed Graft Function

Highlights

  • Living donors are the preferred source of kidneys for transplant as they offer better quality of life, graft- and patient survival [1,2]

  • Minimum recipient post re-perfusion central venous pressure ≥12 mmHg was associated with poor graft function, while intra-operative hypotension was not

  • Delayed graft function and slow graft function had higher incidences of rejection than good function (30% and 36% vs 9%, p=0.012)

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Summary

Introduction

Living donors are the preferred source of kidneys for transplant as they offer better quality of life, graft- and patient survival [1,2]. Despite these superior results, allografts from living donors may still be subject to peri-operative insults, which may lead to both poor short and long-term outcomes. Prior research has focused on central venous pressure (CVP) and arterial blood pressure mostly in the recipient of a deceased donor renal transplant.

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