Abstract
Purpose: The aim of this study is to analyze a ten-year single center experience in liver transplantation in Pernambuco - Northeastern region of Brazil. Methods: Data were retrospectively collected from medical records of 302 patients who underwent Orthotopic Liver Transplantation (OLT) between 1998 and 2008 at Oswaldo Cruz University Hospital, Pernambuco – Brazil. We analyzed just the outcomes and survival curve of 195 adult liver transplantation recipients from deceased donor. Results: Data concern liver donor, surgery technical aspects and liver transplantation recipients’ postoperative evolution are presented and discussed. This center has a significant experience in liver transplantation using conventional technique with no venovenous bypass. Efficient management of liver transplantation practice has made it feasible to keep the cold ischemia time within 6-7 hours. Because of the organ shortage, we have used a large amount of extended criteria liver donor. The survival 1-year rata was 76.4%. Conclusion: It is possible to provide a high-quality public medical assistance in an efficient and continuous manner in less developed areas of Brazil.
Highlights
The first orthotopic liver transplantation (OLT) in Brazil was carried out in 1968.1 In 1993, Lecerda et al performed the first OLT in the Northeastern region of Brazil
Since 1998,2 in this large region of the nation, an effective and uninterrupted OLT center has been functioning in a university hospital (Oswaldo Cruz University Hospital – OCUH).[1]
Among the 302 cases, 195 (64.5%) cases underwent OLT with graft obtained from deceased donors and were considered to the analysis of survival and results
Summary
The first orthotopic liver transplantation (OLT) in Brazil was carried out in 1968.1 In 1993, Lecerda et al performed the first OLT in the Northeastern region of Brazil. Since 1998,2 in this large region of the nation, an effective and uninterrupted OLT center has been functioning in a university hospital (Oswaldo Cruz University Hospital – OCUH).[1] in recent years the amount of centers providing liver transplant (LT) has significantly increased in this country, OCUH LT-Center is still the most productive and experienced across the Northern and Northeastern regions Even today, this is the only center in that region performing OLT in children, and extensively employing conventional OLT technique with no portal systemic shunt. We presented outcomes of 302 cases which have undergone deceased and living donor LT since the program started in our center in April 1998
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