Abstract

Several studies have shown that there is an increase in bilirubin levels, leukocytes, and blood pressure in acute phase strokes. The purpose of this study was to determine the relationship between liver function levels, leucocytes, and blood pressure with the functional outcome of acute stroke. The method was a cross-sectional study with a sample size of 30 people who were selected by consecutive non-random sampling method, clinically proven acute stroke patients, and computed tomography (CT) scan. They were studied at the General Hospital of the Adam Malik Center. Demographic data were analyzed using descriptive statistics. The results showed that all subjects did not differ in terms of demographic characteristics. This study concluds that there is no relation between liver function (total bilirubin, direct bilirubin, indirect bilirubin, serum glutamic oxaloacetic transaminase [AST], serum glutamic pyruvic transaminase [SGPT], alkaline phosphatase [ALP]), leukocytes, and blood pressure with acute stroke functional outcome. The functional outcome in acute hemorrhagic stroke is worse than acute ischemic stroke. Higher levels of liver function, leucocytes, and blood pressure were found in patients with the worse functional outcome though not significantly associated.

Highlights

  • Stroke is the second most common cause of death after heart disease and the third most common cause of disability worldwide (Kenmogne-domning et al, 2018)

  • The collected data was assessed for its association with the functional outcome of acute stroke based on NIHSS and mRS on day 1 and day 14

  • KEMAS 16 (3) (2021) 417-427 the functional outcome of acute stroke based on NIHSS and mRS on days 1 and 14

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Summary

Introduction

Stroke is the second most common cause of death after heart disease and the third most common cause of disability worldwide (Kenmogne-domning et al, 2018). Patients after an ischemic stroke, do movement exercises as early as possible to get optimal improvement. Giving movement exercises to patients should involve the family so that it can be done as often as possible. Movement exercises in stroke patients should be done 6 months after a stroke (Mahmudah, 2012). There is a strong relation between bilirubin levels and the risk of developing ischemic stroke compared to hemorrhagic stroke. Previous studies suggest that this is due to the atherogenic function of bilirubin (Kimm et al, 2009). High glutamate levels and low glutamate oxaloacetate transaminase (GOT) are associated with poor functional outcome on admission. Higher levels of GOT at admission are associated with a good 3-month functional outcome (Ramos-cabrer et al, 2011)

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