Abstract
Background and Aims : Endoglin (CD105) is a 180 kDa transmembrane glycoprotein and a coreceptor for binding to TGFβ1 superfamily existing in two forms, namely membrane endoglin (Eng) and soluble endoglin (sEng) circulating in the blood. It has been demonstrated that Eng might play an important role in the process of liver fibrosis, inflammation, and endothelial dysfunction. However, the precise impact of Eng expression and signalling changes and sEng levels during liver disorders are still unknown.
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