Abstract
Simple SummaryInfectious bronchitis (IB) is one of the more prevalent diseases in poultry, and it is caused by a virus belonging to the Coronaviridae family, the infectious bronchitis virus (IBV), a Gammacoronavirus which is related to the Betacoronavirus SARSCov-2 causing COVID-19 in humans. IB is mainly controlled by biosecurity and vaccines, although, it is a very challenging issue because the viral populations are constantly evolving by several factors. One of these factors is the same vaccines used for IB control, this could explain by recombination, reversion to virulence, or by favoring virus serotype selection. Thus, a human role in the change of viral populations can be identified by the IBV vaccine usage, this must be considered to achieve effective IB control.Infectious bronchitis virus (IBV) remains one of the most important diseases impacting poultry today. Its high adaptive capacity, attributable to the high mutation rate associated with its ssRNA(+), is one of its more important features. While biosecurity procedures and barriers have been shown to be preponderant factors in minimizing the impact of infectious bronchitis (IB), the environment and procedures associated with intensive poultry systems greatly influence the viral population dynamics. High-density poultry flocks facilitate recombination between different viruses, and even with live attenuated vaccines, which can change the dominant circulating field strains. Furthermore, the remaining issue of reversion to virulence gives rise to significant problems when vaccinal strains are introduced in places where their pathogenic variants have not been reported. Under specific conditions, live attenuated vaccines could also change the frequency of circulating viruses and enable replacement between different field strains. In summary, under a comprehensive approach, while vaccination is one of the most essential tools for controlling IB, the veterinarians, farmers, and official services role in its usage is central to minimizing alteration in a malleable viral population. Otherwise, vaccination is ultimately counterproductive.
Highlights
Simple Summary: Infectious bronchitis (IB) is one of the more prevalent diseases in poultry, and it is caused by a virus belonging to the Coronaviridae family, the infectious bronchitis virus (IBV), a Gammacoronavirus which is related to the Betacoronavirus SARSCov-2 causing COVID-19 in humans
Several recombination points have been identified along the entire Infectious bronchitis virus (IBV) genome, where field and vaccine strains have been recognized as parental strains [23]
Given the lack of effective treatment for infectious bronchitis, the best option for poultry farmers and veterinarians is prevention through biosecurity protocols and vaccination schedules aligned with the local reality
Summary
Infectious bronchitis (IB) was first described in 1931 in the USA [1]. The disease is caused by the infectious bronchitis virus (IBV), a Gammacoronavirus belonging to Nidoviral order with a 27.6-kb IBV genome that is ssRNA (+). IBV belongs to the same family as the viruses that cause SARS [11], MERS [12], and the recently-described COVID-19 [13], which spread widely around the world, causing the largest pandemic in modern history. Since all of these human outbreaks have been proven to be of animal origin [14], understanding Coronaviridae dynamics and the veterinarians and farmers role in changing their populations has become one of today’s leading research topics. Higher avidity and antibody levels were observer with a more homogeneous vaccine [20]
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