Abstract
Laser interstitial thermal therapy (LITT) offers a minimally invasive approach to the treatment of both regrowth of brain metastases and/or radiation necrosis following radiosurgery (known together as metastatic in-field recurrence). Current indications for LITT include patients who have KPS >70, have good expected survival or systemic therapy options, and are deemed suitable surgical candidates. While LITT treatment was previously offered when patients required initiation of steroids for symptom management, LITT results have been shown to be better when the lesion is smaller and therefore there is a current trend toward using LITT earlier in the course of the progression of these lesions. While surgical access is less invasive, adverse neurological outcomes following LITT are similar to those encountered in a craniotomy.
Published Version
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