Abstract
Liquid-based cytology (LBC) is transforming the diagnostic landscape of gynecologic oncology, offering enhanced accuracy in the early detection and effective management of cancers like cervical, ovarian, and endometrial. This article provides an in-depth review of the principles underpinning LBC, elaborates on its application in modern gynecologic oncology, and discusses the distinctive advantages that it holds over traditional cytology methods. Furthermore, the article recognizes the potential limitations of LBC, including cost implications and residual challenges with sample interpretation. The discussion also highlights the ability of LBC to synergistically work with additional testing methods such as high-risk HPV DNA testing, which enriches the diagnostic information gathered from each sample. With this comprehensive analysis, the article illustrates the compelling role of LBC in revolutionizing the quality of diagnostic samples and its consequent potential for improving patient outcomes in gynecologic oncology. This exploration paves the way for future research to further harness and optimize the benefits of LBC in advancing gynecologic healthcare.
 Keywords: Liquid-based cytology, Gynecology, Oncology
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