Abstract
A flow cell was designed for simultaneous mass measurements with a quartz crystal microbalance and ellipsometry and was used for studying the adsorption processes of different liposomes, prepared from phospholipids and cholesterol, on both bare and lipid monolayer-covered platinum surfaces. Ellipsometric and gravimetric data were collected during recirculation of liposomes in 0.15 M NaCl. Experiments with ATP-containing liposomes with subsequent lysis were also performed. The results are discussed in terms of both intact liposome adhesion and intact liposome adhesion in combination with planar bilayer formation.
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