Abstract

Background: Following menopause there are changes in values of lipid profile parameters. Abdominal obesity has also been linked to significant metabolic abnormalities including changes in lipid parameter values. So, we designed this study to observe the pattern of lipid profile parameters in postmenopausal central obese women.Objective: To assess the lipid profile status of postmenopausal women with central obesity. Materials and Methods: This cross sectional study was carried out in the department of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh during the period of January 2005 to December 2005. Seventy four postmenopausal women with central obesity and age matched 56 nonobese postmenopausal women were included in the study. Central obesity was defined having waist hip ratio more than 0.8. All statistical analyses were done by SPSS 12.0. p values <0.05 were considered significant. Results: Statistically no significant difference was observed between the central obese women and nonobese women in total cholesterol and LDL-cholesterol levels. But HDL-cholesterol was found lower and triacylglycerol was found higher in postmenopausal central obese women. Conclusion: Dyslipidaemia is a feature of postmenopausal women with central obesity. DOI: http://dx.doi.org/10.3329/jemc.v3i1.13836 J Enam Med Col 2013; 3(1): 08-12

Highlights

  • Postmenopausal women have an increased tendency for gaining weight

  • Seventy four postmenopausal women with central obesity and age matched 56 nonobese postmenopausal women were included in the study

  • There was no difference between the two groups in total cholesterol and LDL-cholesterol levels

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Summary

Introduction

Postmenopausal women have an increased tendency for gaining weight. The decline of endogenous oestrogen, together with physical inactivity is probably the major cause of this phenomenon. Postmenopausal overweight and obesity lead to increased rates of hypertension, diabetes mellitus, coronary heart disease (CHD) and all-cause mortality.[1] Following menopause, adverse changes in lipid profile occur and the levels of several coagulation factors increase.[2]. The lipid profile is a group of tests that are often done together to determine risk of CHD. It includes total cholesterol (TC), HDL-cholesterol, LDLcholesterol and triacylglycerol (TAG). Following menopause there are changes in values of lipid profile parameters. We designed this study to observe the pattern of lipid profile parameters in postmenopausal central obese women. Results: Statistically no significant difference was observed between the central obese women and nonobese women in total cholesterol and LDL-cholesterol levels. Conclusion: Dyslipidaemia is a feature of postmenopausal women with central obesity

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