Abstract

Meeting abstracts Recent studies linking immune signatures in cancer with prognosis have provided unequivocal proof of the essential role of the immune system in tumor pathophysiology. They have also initiated a quest for immune biomarkers that could serve as intermediate endpoints of response to

Highlights

  • Recent studies linking immune signatures in cancer with prognosis have provided unequivocal proof of the essential role of the immune system in tumor pathophysiology

  • Fifty breast cancer (BCa) patients were enrolled with written informed consent

  • Significant correlations among cytokines/chemokines or mi-RNAs in sera were detected among patients but not in healthy donors

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Summary

Introduction

Recent studies linking immune signatures in cancer with prognosis have provided unequivocal proof of the essential role of the immune system in tumor pathophysiology. They have initiated a quest for immune biomarkers that could serve as intermediate endpoints of response to therapy and outcome in cancer. In view of growing evidence for interplay between tumor and systemic circulation, it is critically important to define relationships between the tumor and the periphery in order to reveal novel prognostic and/or predictive biomarkers for cancer

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