Linear Prediction of Nucleotides in a Genome Sequence

Abstract

Nucleotides are organic molecules, which are monomer units that form polymers of nucleic acid ‘deoxyribonucleic acid (DNA)’ and ‘ribonucleic acid (RNA)’. The four nucleotides A, T, G and C get connected by phosphodiester bonds to form strands. Strand formation depends on innumerable factors related to inter and intra cellular parameters and functions. One cannot precisely say that a particular strand gets formed using such and such rules. The infinite possibilities of strand formation cannot be determined experimentally or in the framework of classical genetics. One can alternatively formulate a notion of the “Language of Genomes” wherein one can finitely specify infinite strands. This paper introduces a novel prediction algorithm, which generates possible strands based on available nucleotides statistics.