Abstract
The methods for generation of optical traps in the form of line segments by means of liquid crystal modulators of two types are addressed in the paper, they are a multi-pixel modulator HOLOEYE HEO 1080P and a tunable liquid crystal focusing device (4-channel modulator) developed by the authors. The numerical and experimental assessment of the capture forces of the generated optical trap is fulfilled. The description of manipulation experiments with microobjects, including biological ones, carried out by the optical traps with the intensity distribution in the form of segments is offered.
Highlights
Probable causes for the interest in the optical tweezers applications for the problems of biology and medicine can be the unique capabilities of this toolkit, i.e. the possibility of contactless impact on the objects being studied, resulting in a high sterility, the possibility submicrometer precision of displacement control of the biological objects, etc
In view of the diversity of sizes and shapes of biological objects, as well as a wide range of biomedical problems solvable by means of specified tools, the capture and manipulation of biological objects is fulfilled with the aid of the point optical traps representing sharply focused Gaussian beams, and the traps of other configurations
The most simple, effective and inexpensive technique of the line optical trap (LOT) generation is that based on the use of a cylindrical lens placed in the path of the beam forming the trap
Summary
Probable causes for the interest in the optical tweezers applications for the problems of biology and medicine (see reviews [1,2,3]) can be the unique capabilities of this toolkit, i.e. the possibility of contactless impact on the objects being studied, resulting in a high sterility, the possibility submicrometer precision of displacement control of the biological objects, etc. In view of the diversity of sizes and shapes of biological objects, as well as a wide range of biomedical problems solvable by means of specified tools, the capture and manipulation of biological objects is fulfilled with the aid of the point optical traps representing sharply focused Gaussian beams, and the traps of other configurations. The traps with the intensity distribution in the form of Crescent are proposed by the authors of [4, 5] for the manipulation of biological microobjects Such traps can effectively capture objects while acting on their periphery, not the center. The contour optical traps (in the form of rings, ellipses and C-shaped) formed with the LC focusing device [6] can be used to minimize the radiation effects The advantage of this method for the traps formation is the possibility of real-time control of their shape and size. The results of experiments on manipulations of microscopic objects with formed traps are set forth below
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