Abstract

Multidrug-resistant (MDR) bacteria or superbugs represent a challenge for clinicians and a serious and worsening threat to human health both in community and hospital settings [1]. Physicians routinely encounter patients with infections that are not responding to available treatments and when new antibacterials arrive on the market, bacteria quickly develop resistance. The microorganisms that are mainly involved in the resistance process are the so-called ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa, and enterobacteriaceae), emphasizing their ability to ‘escape’ from commonly used antibacterial treatment [2].

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