Abstract

Light and electron microscopic observations of interstitial cell hyperplasia of testis were made. Some of the hyperplastic interstitial cells in the first case were so atypical that tumorous growth was considered to occur in part.Electron microscopically, the cytoplasm of hyperplastic interstitial cells were filled with vesicles. A large amount of lipochrome pigment granules were found in hyperplastic interstitial cells of the first case, but only scarcely in those of the second case. The pigment granules were assumed to have been induced from mitochondria. Lamellar structures, originating from endoplasmic reticulum, were occasionally found in cytoplasm. Bundles of fibrils were seen scattered in the cytoplasm of some interstitial cells. The bundles were rarely encountered within the lysosomal or pigmental granules, though they were very scarce. They showed occasionally a large aggregation, which might be a precursor of Reinke crystalloid. ACTA PATH. JAP. 20: 387–398, 1970.

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