Abstract
Data are presented on the enantioselectivity and efficiency of ligand-exchange chromatographic resolution of racemic α-amino acids using a polystyrene resin with L-hydroxyproline groups and saturated with Cu 2+. Micropreparative resolution of L,D-leucine is discussed with respect to the degree of sorbent saturation with Cu 2+, elution rate, eluent concentration, operating temperature, column loading and column parameters.
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