Leukocyte dynamics in vaccinated and unvaccinated animals following dual challenge with Bovine Viral Diarrhea Virus-Mannheimia haemolytica model to compare vaccine efficacy in calves

Abstract

Bovine respiratory disease continues to be the greatest threat to calf health. One of the common recommendations is to vaccinate young beef and dairy calves at 30-60 days of age to provide protection at weaning or when commingled. The study objective was to determine whether there were any dif­ferential leukocyte changes that could be measured following a dual challenge with Bovine Viral Diarrhea Virus (BVDV) and M. haemolytica ~5 months after vaccination.