Letters to the Editor

Abstract

In reply to Dr. Ehrlich's questions, we only wish that life would be as simple as he implied. The association of increased peripheral venous insulin values with islet cell adenoma is by no means universal in adults. In a child with multiple islet cell adenomata (Pediatrics, 39:59, 1967) , fasting plasma insulins as well as those following glucose, tolbutamide, and leucine, were not abnormally elevated. No other studies of peripheral or portal plasma insulin levels in infants or children with islet cell adenoma are known to us.