Abstract
To the Editor: Recent hypertension research has shown that large artery compliance is an important determinant of systolic pressure, pulse pressure, and cardiovascular disease. Many methods exist to determine compliance or its inverse, arterial stiffness; the time constant of the aortic pressure decay in diastole, the ratio of stroke volume over pulse pressure, and pulse wave velocity are among the most used. These methods require either invasive measurements or 2 simultaneous measurements and are not practical to use in epidemiological studies or in night–day variations. Dolan et al1 recently suggested the use of the Ambulatory Arterial Stiffness Index (AASI), defined as 1 minus the slope of the (linear) relation between diastolic and systolic pressure, as a measure of arterial stiffness. The AASI is easy to …
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