Abstract
Background Transcatheter aortic valve implantation (TAVI) has become a common procedure for high-risk patients with severe aortic stenosis. Aortic regurgitation (AR) is commonly seen after TAVI, but little is known about how it evolves over time. Similarly, the impact of TAVI on left ventricular (LV) function, LV volumes and mass is not well defined.Paravalvular aortic regurgitation (AR) is frequent after TAVI. Yet, little data is available about temporal changes of AR and the impact of TAVI on left ventricular (LV) function and dimensions. We used cardiac MRI to evaluate LV function, volumes and mass, the occurrence and degree of AR in the early and medium-term follow-up after TAVI.
Highlights
Transcatheter aortic valve implantation (TAVI) has become a common procedure for high-risk patients with severe aortic stenosis
At baseline MRI, the median left ventricular (LV) ejection fraction was 58.0%, which improved significantly at follow-up to 63.4%
The changes in LV function, volume and mass observed in the oberall cohort were not present in the subgroup of patients with relevant Aortic regurgitation (AR) at baseline MRI: the mean ejection fraction only showed a trend to improvement (48.8 ± 15.7% vs. 50.9 ± 15.0%, p=0.08) whereas the mean LV end-diastolic volume (183.3 ± 50.1 ml vs. 184.6 ± 55.9 ml, p=0.90) and LV mass (174.9 ± 25.8 g vs. 172.8 ± 41.3 g, p=0.84) were almost identical at baseline and follow-up
Summary
Left ventricular remodelling and prosthetic valve function after transcatheter aortic valve implantation: A serial cardiac magnetic resonance imaging study. Constanze Merten1*, Hans Beurich, Dirk Zachow, Mohamed El-Mawardy, Gert Richardt, Mohamed Abdel-Wahab
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