Abstract

Background Percutaneous edge-to-edge repair with MitraClip has been recommended as an alternative to conventional mitral valve repair in symptomatic severe mitral regurgitation at very high surgical risk. Data on the impact of MitraClip on left ventricular volumes are scarce. Therefore we aimed to assess left ventricular remodeling following MitraClip. Methods Consecutive patients scheduled for MitraClip were prospectively studied. Patients with pacemaker or ICD were excluded. Transthoracic echocardiography and CMR at 1.5 Tesla were performed before and 6 months after MitraClip procedure. Left ventricular volumes were measured using transthoracic echocardiography (biplane Simpson’s method) and short-axis SSFP CMR images covering the left ventricle. Mitral insufficiency was graded using color Doppler flow mapping (grade 1-4). Results

Highlights

  • Percutaneous edge-to-edge repair with MitraClip has been recommended as an alternative to conventional mitral valve repair in symptomatic severe mitral regurgitation at very high surgical risk

  • Consecutive patients scheduled for MitraClip were prospectively studied

  • Negative remodeling occurred in both patients with MitraClip failure

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Summary

Introduction

Percutaneous edge-to-edge repair with MitraClip has been recommended as an alternative to conventional mitral valve repair in symptomatic severe mitral regurgitation at very high surgical risk. Left ventricular remodeling following percutaneous edge-to-edge repair using Mitraclip Bernard P Paelinck1*, Tom Vandendriessche2, Dina De Bock1, Paul M Parizel3, Inez E Rodrigus1, Claeys J Marc2 Background Percutaneous edge-to-edge repair with MitraClip has been recommended as an alternative to conventional mitral valve repair in symptomatic severe mitral regurgitation at very high surgical risk.

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