Abstract
Background The effect of transcatheter aortic valve implantation (TAVR) on left ventricular remodelling early following valve implantation has not previously been evaluated using cardiac magnetic resonance (CMR). Early left ventricular mass (LVM) regression (assessed using echocardiography) has been linked to a 50% reduction in rehospitalisation in the first year following TAVR. We sought to establish using CMR, the reference standard non-invasive imaging technique for LVM quantification, whether LVM regression occurs early post-TAVR.
Highlights
The effect of transcatheter aortic valve implantation (TAVR) on left ventricular remodelling early following valve implantation has not previously been evaluated using cardiac magnetic resonance (CMR)
At a median of 5 days following TAVR, mean left ventricular mass (LVM) regressed by approximately 12% from 129.5± 32.5g to 114.2±31g and indexed LVM (LVMi) reduced from 69.4 ± 15.2g/m2 to 61.3±15.1g/m2 (Graph 1)
There was no significant change in indexed left ventricular diastolic volume (96.9 ± 24.5 to 96.8 ± 19.3ml/m2, p=0.79), LV ejection fraction (54.0± 14.6 to 58.4 ± 27.4%, p=0.49) or indexed left atrial volume (71.5±22.6 to 67.7±22.1ml/ m2, p=0.43)
Summary
The effect of transcatheter aortic valve implantation (TAVR) on left ventricular remodelling early following valve implantation has not previously been evaluated using cardiac magnetic resonance (CMR). Left ventricular mass (LVM) regression (assessed using echocardiography) has been linked to a 50% reduction in rehospitalisation in the first year following TAVR. We sought to establish using CMR, the reference standard non-invasive imaging technique for LVM quantification, whether LVM regression occurs early post-TAVR
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