Abstract
Objective: To compare the rate and severity of LVH in blacks and whites with spontaneous ICH. Background Left ventricular hypertrophy (LVH) is a reversible structural heart condition that independently increases the risk of stroke, vascular disease and death. In addition to being the most common cause of LVH, hypertension (HTN) is the most common cause of spontaneous intracerebral hemorrhage (ICH). As blacks (B) have earlier onset, higher frequency, and more severe HTN, we hypothesized that blacks with ICH may have higher rates of LVH than their white (W) counterparts. Design/Methods: A retrospective cross-sectional descriptive analysis of patients presenting with spontaneous ICH from July 2008 to December 2010 was performed. Transthoracic echocardiogram (TTE) must have been completed during the same hospitalization. Baseline demographics, clinical characteristics, and TTE results were collected and analyzed using Chi square and Mann-Whitney U. Results: 119 consecutive patients were screened. 82 (68%) met inclusion criteria. Subjects were 57% male, 70% black with a median age of 58 (19-90), and median NIHSS 15 (IQR 6,21). Blacks were younger (p=.02), presented with higher blood pressure (p Conclusions: In our single center experience, LVH was identified in a substantial number of ICH patients. Further, blacks with ICH had more frequent and severe LVH. We suggest that TTE should be part of the routine work-up of patients with ICH to ascertain and stage hypertensive heart disease, because effective treatment of LVH may require tailoring of antihypertensive medications to reduce the risk of subsequent vascular events. Disclosure: Dr. Albright has nothing to disclose. Dr. Martin-Schild has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Siegler has nothing to disclose. Dr. Denny has nothing to disclose. Dr. Alexandrov has nothing to disclose. Dr. Martini has nothing to disclose. Dr. Martin-Schild has nothing to disclose.
Published Version
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