Abstract
BackgroundTwo-dimensional speckle-tracking echocardiography (2D-STE) enables objective assessment of left atrial (LA) deformation through the analysis of myocardial strain, which can be measured by different speckle-tracking software. The aim of this study was to compare the consistency of 3 different commercially available software, which include vendor-specific software for measuring left ventricle (VSSLV), vendor-independent software packages for measuring LV strain (VISLV) and vendor-independent software packages for measuring LA strain (VISLA).MethodsSixty-four subjects (mean age: 44 ± 16 years, 50% males) underwent conventional echocardiograms using a GE Vivid 9 (GE Ultrasound, Horten, Norway) cardiac ultrasound system. Standard apical 4 and 2 chamber views of the left atrium were obtained in each subject with a frame-rate range of 40–71 frames/s. LA strain during the contraction phase (Sct), conduit phase (Scd), reservoir phase (Sr = Sct + Scd) were analyzed by 2 independent observers and 3 different software.ResultsSct, Scd, Sr were, respectively, − 11.26 ± 2.45%, − 16.77 ± 7.06%, and 28.03 ± 7.58% with VSSLV, − 14.77 ± 3.59%, − 23.17 ± 10.33%, and 38.23 ± 10.99% with VISLV, and − 14.80 ± 3.88%, − 23.94 ± 10.48%, and 38.73 ± 11.56% when VISLA was used. A comparison of strain measurements between VSSLV and VIS (VISLV and VISLA) showed VIS had significantly smaller mean differences and narrower limits of agreement. Similar results were observed in the coefficient of variation (CV) for measurements between VSSLV and VIS (VISLV and VISLA). Comparison of the intra-class correlation coefficients (ICCs) indicated that measurement reliability was weaker with VSSLV (ICC < 0.6) than with VIS (VISLV and VISLA) (ICC > 0.9). For intra-observer ICCs, VISLA > VSSLV = VISLV. For inter-observer ICCs, VSSLV > VISLA > VISLV.ConclusionsSoftware measurement results of LA strain vary considerably. We recommended not measuring LA strain across vendor platforms.
Highlights
left atrial (LA) is of hemodynamic importance for overall cardiac performance through reservoir, conduit, and booster pump functions [1,2,3]
To assess the comparability between paired software (VSSLV-vendor-independent software packages for measuring LV strain (VISLV), vendor-specific software for measuring left ventricle (VSSLV)-vendor-independent software packages for measuring LA strain (VISLA), and VISLVVISLA), the overall ratio of non-significance was calculated for each specific software, and for each pair
Intra-observer and inter-observer Coefficient of variation (CoV) for differences of strain during the contraction phase (Sct) and Strain during reservoir phase (Sr) measured by VSSLV were significant Intra-observer and inter-observer CoVs for differences of Sct measured by VISLV had no significant differences (p > 0.05) Intra-observer and inter-observer CoVs for differences of strain measured by VISLA, were of no significant differences (p > 0.05)
Summary
LA is of hemodynamic importance for overall cardiac performance through reservoir, conduit, and booster pump functions [1,2,3]. The evaluation of LA function by Doppler analysis can be affected by left ventricle (LV) dysfunction, and is Because of the aforementioned drawbacks, there is increasing interest in speckle-tracking echocardiography (2019) 17:9. There was no specialized 2D-STE software for the assessment of LA deformation. Studies evaluating LA function used software designed for evaluation of the left ventricle (LV) [14]. Two-dimensional speckle-tracking echocardiography (2D-STE) enables objective assessment of left atrial (LA) deformation through the analysis of myocardial strain, which can be measured by different speckletracking software. The aim of this study was to compare the consistency of 3 different commercially available software, which include vendor-specific software for measuring left ventricle (VSSLV), vendor-independent software packages for measuring LV strain (VISLV) and vendor-independent software packages for measuring LA strain (VISLA)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
