Abstract
Summary We assess left atrial scar using late gadolinium enhancement (LGE) with isotropic spatial resolution of 1.4mm 3 by using highly accelerated LOST [1] reconstruction. Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia [2]. Pulmonary vein isolation (PVI) using radiofrequency (RF)-ablation is the leading treatment for AF. Recently, LGE imaging of the LA has been used to identify atrial wall scar due to RF-ablation [3]. However, current LGE methods have limited spatial resolution that substantially impact assessment of scar in the complex geometry of PVs and LA. In this study, we sought to utilize prospective random k-space sampling and LOST [1] for accelerated LGE imaging, where reduction in imaging time was traded-off for improved isotropic spatial-resolution.
Highlights
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia [2]
LOST-reconstructed high-resolution, and standard LGE images were scored by two blinded readers for diagnostic value, presence of LGE(yes/no); and image quality in axial(Ax), coronal(Co) and sagittal (Sa) views (1=poor,4=excellent)
LGE was visually present in 14 of the remaining 20 patients based on standard-LGE images, and 12 based on LOST-reconstructed ones
Summary
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia [2]. Pulmonary vein isolation (PVI) using radiofrequency (RF)-ablation is the leading treatment for AF. LGE imaging of the LA has been used to identify atrial wall scar due to RF-ablation [3]. Current LGE methods have limited spatial resolution that substantially impact assessment of scar in the complex geometry of PVs and LA. We sought to utilize prospective random k-space sampling and LOST [1] for accelerated LGE imaging, where reduction in imaging time was traded-off for improved isotropic spatial-resolution
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