Abstract
A reversed-phase column liquid chromatographic method for the separation and quantification of mescaline present in “peyote” has been developed using a Symmetry C18 column and isocratic profile. The method can be utilised for the quantitative determination of other alkaloids. This method is economical in terms of the time taken and the amount of solvent used for each analysis. The validity of the method with respect to analysis was confirmed by comparing the UV spectra of peak with the reference compound (mescaline) using a photodiode array detector. The assay method described is simple, rapid and accurate, and may form part of future drug authentication protocols.
Published Version
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