Abstract
ABSTRACTBacteria‐related infection is a significant problem for the implant materials, which would lead to the failure of the implants. Thus, the surface functionalization for the implant with bacterial inhibition properties would be urgently needed. However, surface inertness and structure complexity are barriers to the surface modification of the 3D‐printed polymer implant. For this reason, the efficiency of antibiotic‐loaded polyelectrolyte multilayers on 3D‐printed resin is investigated. The obtained samples are characterized by various techniques. Antimicrobial test results show that a 99.9% eradication rate against Staphylococcus aureus (S. aureus) could be achieved by antibiotic‐loaded samples. However, the cytocompatibility test shows that the samples also exhibit mild cytotoxicity due to the rapid release of gentamicin sulfate (GS); thus, further work is needed to reduce the side effects of the antibiotics.
Published Version
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