Lateralization parallels study in Uzbekistan: Comparison of changes between lateral and medial temporal lobe epilepsy

Abstract

We aimed to study the comparative changes between medial and lateral temporal lobe epilepsy (MTLE and LTLE). The study was based on the results of examination of 48 patients with medial and lateral temporal epilepsy, who were on a stationary examination in the department of neurology of the first TMA clinic from 2016 to 2018. During Video-EEG-monitoring we recorded 114 seizures of various types. The most significant lateralizing features in this form of epilepsy were one-sided wrist automatism, a dystonic brushes and an unbalanced turn of the head. The most valuable lateralizing sings of the epileptogenic focus for this form of epilepsy are the dystonic setting of the wrist (85.7%, p = .02), the inverting turn of the head (88.9%, p = .02) and after-seizure aphasia (100%). Also for this group, the prevalence of localization of pathological disturbances in the region of the anterior temporal electrode was found (75,0%, p = .02 in comparison with the LTLE group), and in cases of presence of additional zones of localization - their registration in the contralateral temporal lobe (63,6%, p = .02 in comparison with the LTLE group). Taking into account the revealed features of seizures, differential diagnosis between lateral and medial forms of temporal epilepsy can be based on the lateralizing sings.