Latent Celiac Disease and Undifferentiated Connective Tissue Disease Association

Abstract

Celiac Disease (CD), is a common autoimmune disorder of the small intestine. Here we present a case in which has Latent Celiac Disease (LCD) and Undifferentiated Connective Tissue Disease (UCTD) association. The patient presented with abdominal pain, constipation, bloating, joint pain and wounds in the mouth as complaint. The patient were detected that iron, vitamin D and B12 deficiency, ANA, Antigliadin Ig G, Tissue transglutaminase IgG and HLA-DQ2 positivity. The clinical, laboratory, and interventional results of the patient were not fully compatible with a specific rheumatic disease pattern. No pathology was detected in the esophagogastroduodenal endoscopy but the gluten-free diet, based on clinical findings, provided clinical improvement. It is known that autoimmune or rheumatologic disorders are more common in celiac patients than in the normal population. We presented this case as a case of UCTD accompanying LCD to bring a different perspective to the pathophysiology of Celiac disease.