Abstract
Celiac disease (CD) is a common immune-mediated disorder that affects approximately 1% of Caucasians and develops in genetically susceptible subjects after the ingestion of gluten proteins present in wheat, barley, and rye.1 Although historically CD was defined by small-bowel damage and subsequent malabsorption, more recently it has been recognized as a multisystem disorder that may affect other extraintestinal organs, such as the skin, heart, nervous system, and liver.2 CD has some characteristics that have been described in typical autoimmune disorders but CD is unique among the autoimmune diseases because the autoantigen (tissue transglutaminase) and environmental trigger (gluten) are known (Table 1).3 Table 1 Common Characteristics Between Typical Autoimmune Disease and CD
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
