Abstract
Obesity is associated with Metabolic Syndrome (MetS) and high cardiovascular risk as well as inflammation. Bariatric surgery is the most effective treatment of obesity and cardiovascular risk reduction. The aim of this research was to evaluate the Laparoscopic Sleeve Gasterectomy (LSG) effect on cardiometabolic risk factors, proinflammatory cytokines and oxidative stress markers in 25 women with morbid obesity (body mass index=45.4 ± 2.0 kg/m2). LSG is mini-invasive operation without radical reconstruction of gastrointestinal tract. It was established that after LSG there were no activation of inflammation, in contrast, there was reduction of proinflammatory cytokines (interleykin-6, tumor necrosis factor-alpha) and C-reactive protein in the blood at early (7th day) and late (3 month) period after operation. LSG led to a decrease in body weight and reduces cardiometabolic risk by normalizations of lipidomic profile (high-density lipoprotein cholesterol, triglyceride concentration in blood), optimizing the visceral fat tissue metabolism and reduction of inflammation and oxidative stress.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
