Laparoscopic living donor hepatectomy in living donor liver transplantation: a Meta-analysis

Abstract

Objective To systematically evaluate the role of laparoscopic living donor hepatectomy in living donor liver transplantation (LDLT). Methods A systematic literature search was conducted on Medline-Pubmed, Embase, Cochrane Library to find studies on laparoscopic living donor hepatectomy for LDLT. All extracted data were analyzed using the RevMan 5 software. Results Ten studies with a total of 1 059 participants were included in this analysis. Laparoscopic donor hepatecomy (LDH) was associated with significantly less intraoperative blood loss [SMD=-0.39, 95% CI (-0.73, -0.05), P 0.05). There were no differences on the harvested liver graft size, ischemic time, recipient postoperative liver function and complications between the two groups (P>0.05). Conclusions Laparoscopic hepatectomy in li-ving donor is a safe procedure for graft-harvesting, which improved the clinical outcomes of the donor, liver graft and recipient in LDLT. It has also the advantages of reduced blood loss, low peak levels of postoperative total bilirubin and short hospitalization stay. Key words: Living donor liver transplantation; Laparoscopy; Safety; Complication; Meta-analysis