Abstract
Probiotics are increasingly being used as a nutritional supplement by athletes to improve exercise performance and reduce post-exercise fatigue. Lactobacillus salivarius is a natural flora in the gastrointestinal tract of humans and animals. Lactobacillus salivarius subspecies salicinius (SA-03) is an isolate from the 2008 Olympic women’s 48 kg weightlifting gold medalist’s gut microbiota. In this study, we investigated its beneficial effects on physical fitness. Male ICR mice were divided into four groups (n = 10 per group) and orally administered with SA-03 for 4 weeks at 0, 2.05 × 109, 4.10 × 109, or 1.03 × 1010 CFU/kg/day. Results showed that 4 weeks of SA-03 supplementation significantly improved muscle strength and endurance performance, increased hepatic and muscular glycogen storage, and decreased lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise. These observations suggest that SA-03 could be used as a nutritional supplement to enhance exercise performance and reduce.
Highlights
Non-pathological / physiological fatigue can be further characterized as being caused by central and peripheral mechanisms, and both of these mechanisms play important roles in the physiological effects of exercise process, type, intensity, and duration [1,2]
Recent studies have shown that probiotic supplements can improve athletic performance in various ways through athletes and individuals who exercise with discrete probiotic strains and pointed out that they could effectively improve exercise performance and reduce fatigue indicators [27]
We found that four weeks of SA-03 supplementation significantly decreased one of the fatigue indexes, lactate (Table 2), probably by expediting its conversion to butyrate and to acetyl-CoA, which is used in the Krebs Cycle to generate adenosine triphosphate (ATP) [31]
Summary
Non-pathological / physiological fatigue can be further characterized as being caused by central and peripheral mechanisms, and both of these mechanisms play important roles in the physiological effects of exercise process, type, intensity, and duration [1,2]. Previous studies have shown that probiotics have anti-obesity effects [7], can lower cholesterol levels [8], anti-inflammation [9], anti-bacterial [10], anti-oxidation [11], anti-proliferative and anti-carcinogenic activities [12]. They have been shown to enhance carbohydrate metabolism to produce SCFA [13] such as butyrate, which is converted to acetyl-CoA for production of adenosine triphosphate (ATP) to provide energy [14]. Past research has shown that, probiotic supplements can effectively improve exercise performance and reduce fatigue biochemical values after exercise [15,16]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
