Abstract
IN A ONE-YEAR PERIOD, we observed lactic acidosis in five oncology patients in association with the use of total parenteral nutrition. There are multiple previous reports of lactic acidosis in patients with cancer, usually leukemia or lymphoma. 1,2 The association with TPN has been noted in two adult patients and has been described in one pediatric patient receiving 10% glucose infusion. :~ ~ The relatively high risk for lactic acidosis in pediatric patients with advanced cancer when receiving TPN has not been previously stressed.
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