Abstract
Lack of Transmission of Vaccinia Virus
Highlights
A concern in such programs is the potential for unintended spread of the vaccine virus from the primary vaccinee to contacts who may be at the greatest risk of having adverse reactions resulting from secondary transmission [2,3]
We present the first reported attempt to recover live vaccinia virus from the homes of recently vaccinated persons
We hypothesized that live vaccinia virus shed from the skin reaction could not be recovered in the natural environment, and as a result, constitutes a limited risk for contact transmission
Summary
A concern in such programs is the potential for unintended spread of the vaccine virus (vaccinia) from the primary vaccinee to contacts who may be at the greatest risk of having adverse reactions resulting from secondary transmission [2,3]. Contact spread of the live attenuated vaccinia virus is considered the predominant method of secondary transmission. The conventional methods of preventing a secondary transmission event in the household of a smallpox vaccine recipient include the use of bandages and long sleeves to limit direct contact with the lesion and immediate hand-washing when contact occurs [4].
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