Abstract
Aim Peripheral vascular disease (PVD) and coronary artery disease (CAD) are, in many cases, asymptomatic and not usually diagnosed. The timely diagnosis of peripheral vascular diseases can act as an indicator or practical evidence of CAD. Therefore, this study was conducted to determine the relationship between interarm systolic blood pressure difference (IASBPD) and severity and number of coronary artery stenosis. Methods The samples in this cross-sectional study consisted of 578 patients who were candidates for coronary angiography, with an average age of 57.5 ± 10.5 years. Patients were classified according to CAD and number and severity of coronary artery stenosis. The relationship between IASBPD and presence or lack of CAD as well as the number and severity of coronary artery stenosis was studied. The sensitivity, specificity, and positive predictive value of IASBPD index were calculated for the detection of CAD using the Kappa coefficient. Results There was no statistically significant relationship between IASBPD, CAD, and severity and number of coronary artery stenosis. This index had low sensitivity and predictive value in the diagnosis of CAD and stenosis in coronary arteries in comparison with angiography. Conclusion The results showed that the IASBPD index cannot be a valid criterion for the diagnosis of CAD as well as the number and severity of coronary artery stenosis. More studies with larger sample sizes and different designs are needed in this regard to achieve more conclusive results.
Highlights
Peripheral vascular disease (PVD) and coronary artery disease (CAD) are two major problems of modern medicine [1,2,3,4]
Based on the CAG results, the patients were divided into two groups of without CAD and with CAD
To determine the predictive power of interarm systolic blood pressure difference (IASBPD) index in diagnosing CAD, kappa coefficient was used
Summary
Peripheral vascular disease (PVD) and coronary artery disease (CAD) are two major problems of modern medicine [1,2,3,4]. Erefore, CAD and cerebrovascular diseases are commonly seen with PVD [4]. More than one-third of patients have CAD in addition to PVD, and up to a quarter of them have carotid artery disease. In addition to clinical examinations and history-taking, invasive procedures such as angiography and noninvasive tests such as Ankle Brachial Index and interarm systolic blood pressure difference (IASBPD) are used to identify and detect PVD [6, 7]. Considering the high prevalence of CVD, presenting and introducing a criterion is very valuable and effective in the screening and diagnosis of PVD and CAD in asymptomatic patients and those who are at the early stages
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