Abstract
Gaseous essential oils inhibited dose-dependently the flying ability of houseflies but not the mobility of German cockroaches. GC analysis of the extract of organisms treated revealed that gaseous oil was accumulated in the body of the housefly, similar to filamentous fungus, but not in the body of the German cockroach. Most of the essential oils examined retarded dose-dependently the germination of kidney bean by suppressing the growth of radicle and hypoctyl, but only the oil that was not metabolized in vivo inhibited the growth of epicotyl. When systemically exposed for a short period, gaseous essential oils were efficiently distributed in the body of mice and rats through percutaneous absorption, and accumulated in the brain. The aldehyde components were readily converted into the corresponding carboxylic acids in vivo. Cytotoxicity of essential oils against Chinese hamster cells was changed by gaseous and solution contacts. Continued gaseous exposure of high dosages of essential oils to mice for one week caused no pathological abnormality, though body weight gain was suppressed at an early stage. Finally, future prospects of anti-infectious aromatherapy in the gaseous state are discussed.
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