Abstract
Summary The second half of the 20th century was what it is necessary to call the gold age of the antibiotherapy, incontestable medical success. For several decades, the treatment of bacterial infectious diseases calls antibiotics which had provoked a huge hope. Today, with the appearance of microbes resistant to almost all antibiotics “superbug”, some infections, notably nosocomial infections, have sometimes dramatic consequences. The treatment of the bacterial infectious diseases with the aid of specific viruses, called bacteriophages, is offered as a possible “alternative”. This treatment, phage therapy, is not new, but it is misread, sometimes condemned by negative prejudices and its possible return will not be able to be made without a reappraisal. This review offers to take stock of the situation of last knowledge on the bacteriophages therapeutic and to introduce the phage therapy as a practical point of view in a modern context. These developments and our personal experience lead us to propose to use both therapies simultaneously.
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