Abstract
Today, we are facing the spread of antibiotic resistance in various microbial communities. Also, researchers are using new methods to replace conventional treatments to prevent chronic bacterial infections. Hence, the used of phages or bacterial contaminant particles are now used as an effective method in the treatment of many infectious diseases. Several studies have suggested that the use of bacteriophages is effective in treating some bacterial diseases. Therefore, the present study was performed to evaluate phage therapy studies against infections caused by bacterial infections. The use of bacteriophages as new targets in the treatment of bacterial diseases restricts the development of infectious diseases. Bacteriophages can provide a new perspective in the development of new drugs to reduce the rate of bacterial infections. Also, it seems more research should be done in this field and more developed techniques should be used to evaluation of new phages.
Highlights
Bacteriophages were firstly introduced in 1886 by Hankin
In 1919, bacteriophages were used to treatment of bacterial infections in Eastern Europe and the former Soviet Union
Researchers were able to discover the antibiotic properties of phages against bacterial infections [18]
Summary
Bacteriophages were firstly introduced in 1886 by Hankin. in 1931, two researchers, including Felix d'Hrelelle and George Eliava used bacteriophages to treat and prevent Vibrio cholera [1]. In 1940, the Eli Lilly Institute produced seven phage products in the United States against bacterial infections, including Streptococcus, Staphylococcus, and Escherichia coli. From 1939 to 1940, the Finnish campaign reported the use of phage produced by the Eliava Institute against Staphylococcus and Streptococcus to the improvement of wounds and surgery. In this regard, the discovery of penicillin by Alexander Fleming and the problems of phage therapy caused phage therapy to be forgotten for two decades [4]. The present study was performed to use bacteriophages in the treatment and control of bacterial infectious diseases in a very key way and tries to provide a comprehensive perspective [12]
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