Abstract
Osteoporosis is a chronic progressive disease in which bone mass is reduced and a progressive deterioration of the microarchitectural structure of bone occurs. Osteoporosis has a strong relationship to the incidence of fractures. Goal of the diagnosis is to identify patients with low bone mass and at risk for fractures, permitting proper medical care. DXA is considered by WHO the diagnostic “gold standard”, it has been shown to be a robust and accurate technique to determine fracture risk and response to medical therapy. QUS e QCT are useful in specific cases, but have limited clinical indications. Current research efforts are focused on determining the potential role of high-resolution bone imaging (MD-CT and 3T MRI) in the evaluation of cortical and cancellous bone microarchitecture.
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