Abstract
Recently, the use of pharmacotherapeutic agents of plant origin is increasing as an alternative to synthetic chemical drugs. Although quite a lot of plant-based bioactive ingredients have been reported, the bioactive molecule chyrisin, which is found in some products such as blue passionflower, honey and propolis, has become a remarkable phytochemical in recent years. Chrysin is an important flavonoid that stands out with its strong antioxidant, anticarcinogenic and anxiolytic properties as well as having many different pharmacological effects. In this review, it is aimed to give information about the physicochemical, pharmacokinetic, pharmacodynamic properties of chrysin and its protective and beneficial properties in various diseases.
Highlights
Veteriner Farmakoloji ve Toksikoloji Derneği BülteniBulletin of Veterinary Pharmacology and Toxicology Association e-ISSN: 2667-8381
Dietary supplements from plant origin possess many pharmacological properties and are able to protect and cure diseases in humans and animals (Khan and Sultana, 2011).Flavonoids constitute a group of important bioactive substances found in plants
The results indicated that chrysin improves neural function and this may be associated with inhibition of inflammation and the inducible Nitric Oxide Synthase (iNOS) pathway
Summary
Bulletin of Veterinary Pharmacology and Toxicology Association e-ISSN: 2667-8381. Günümüzde sentetik kimyasal ilaçlara alternatif olarak bitki kökenli farmakoterapötik ajanların kullanımı artmaktadır. Oldukça fazla bitki bazlı biyoaktif bileşen bildirilmiş olsa da mavi çarkıfelek, bal ve propolis gibi bazı ürünlerde bulunan biyoaktif molekül krisin, son yıllarda dikkat çekici bir fitokimyasal haline gelmiştir. Birçok farklı farmakolojik etkiye sahip olmasının yanı sıra güçlü antioksidan, antikanserojenik ve anksiyolitik özellikleri ile öne çıkan önemli bir flavonoiddir. Farmakokinetik, farmakodinamik özellikleri ve çeşitli hastalıklarda koruyucu ve faydalı özellikleri hakkında bilgi verilmesi amaçlanmıştır.
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