Abstract
Quantitative leakage control is used during isolated limb perfusion in cases of high-dosage chemotherapy. By positioning scintillation probes across the heart and the extra-corporal circulatory system we can measure the distribution of the 111In-marked erythrocyte. The rate of the leakage can then be determined from the cyclical measurements given. This indicates the quantitative volume crossover from the introduction of the cytostatic substances into the perfusate, and is the basis for any further necessary interventions during the procedure.
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