Abstract
Background and aims: Chromoendoscopy involves the topical application of stains or pigments to improve tissue localization, characterization, or diagnosis during endoscopy. In the diagnosis of colonic polyps, pit pattern analysis, which has previously been described by chromomagnification endoscopy, is used. In this study, we evaluated the accuracy of chromomagnifying endoscopy by comparison of results with histological analysis of colonic polyps. Materials and Methods: Totally 47 polyps of 35 selected patients were evaluated. Polyps were stained with 0.4% indigo-carmine dye and examined under microscope with a power magnification of 100x. After the pit pattern analysis according to Kudo classification was completed, histologic examination was performed. The endoscopic and histologic diagnoses were compared and diagnostic accuracy was determined. Results: Seven polyps were nonneoplastic (type I-II pattern) and 40 polyps were neoplastic (type III-V pattern) according to pit pattern analysis. The diagnostic accuracy was 83.3- 100% in the polyps predicted to be neoplastic. The diagnostic accuracy was lower in the polyps predicted to be nonneoplastic, but there was no polyp with neoplastic histology in this group. Conclusion: In colonic polyps, we predicted histology with high diagnostic accuracy using chromomagnification endoscopy. Chromoendoscopy should be a part of conventional colonoscopy, and magnification should be used as well during the evaluation of target lesions.
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