Known and unknown aspects of the use of propylene glycol and glycerin and possible solutions

Abstract

Traditionally, the main focus of the use of all known energy products (energy additives) in modern dairy farming is designed for one or another energy-rich glucoplastic component. It is quite obvious that with this, animal breeders are trying to fill the energy needs of the cows' body during stressful periods when they reach a high level of dairy productivity. No matter how energy-rich the feed energy additives are, they are all aimed at achieving maximum productivity, while health issues remain in the background. For example, the extensive experience of using propylene glycol and glycerin as feed energy products for cows did not reduce the problem of fatty hepatosis in any way. However, how to solve the problem of energy deficiency, including reduced risk of side effects of feed propylene glycol and glycerin? What is the innovation of the approach? The thing is that the main emphasis is not at all on the glucoplastic component, no matter how "rich" it is with energy, but on the activation of energy metabolism, in particular the activation of the most productive aerobic pathway of energy synthesis. And here's why. In terms of the efficiency of energy synthesis, the aerobic pathway surpasses the anaerobic pathway by 19 times. Glucose synthesis during lipolysis is much more difficult and much longer. Before turning into an energy substrate (glucose), glycerin is synthesized from fats. If the lipolysis process takes place under conditions of insufficient oxygen supply, then this is accompanied by the formation of a large number of acidic by-products-ketoacids. With a large accumulation, they become poisonous to the body. Thus, in conditions of insufficient oxygen supply of cells with oxygen, energy metabolism follows the least productive path with the formation of an excess of lactate and keto acids problematic for the body. It is this vital aspect that has been taken into account and technically implemented using the example of feed propylene glycol and glycerin. The basis of the innovative approach is the activation of energy exchange. Succinates are used as activators of energy metabolism. Cyanocobalamin is used as an activator of digestive processes and hematopoiesis. Everything is technologically simple, economically affordable, environmentally safe and absolutely harmless to the body of animals. In terms of production, this approach is an alternative to the commercial interest of manufacturers and suppliers of energy feed additives interested in the constant (daily) introduction of "energy-rich" glucoplastic agents into the diet. Moreover, the use of such energy feed additives, for example, as fat-like energy products, is very dangerous for animal health. How to make them safe is shown in this paper.