Abstract

We review the mechanisms underlying material ejection in pulsed laser ablation of biological tissues, with special emphasis on the thermodynamics and kinetics of phase transitions and their modifications arising from the presence of a tissue matrix.

Highlights

  • It is known that efficient laser ablation of biological tissues using pulsed IR laser irradiation is always associated with material ejection

  • Special emphasis is laid on the thermodynamics and kinetics of phase transitions and their modifications arising from the presence of a tissue matrix

  • The results presented here will be used in two other articles of this proceedings volume to analyze the dynamics of free-running and Q-switched Er:YAG laser ablation, In our analysis of phase transitions, tissue is viewed as material consisting of cells that reside in and attach to an extracellular matrix (ECM)

Read more

Summary

INTRODUCTION

It is known that efficient laser ablation of biological tissues using pulsed IR laser irradiation is always associated with material ejection. The results presented here will be used in two other articles of this proceedings volume to analyze the dynamics of free-running and Q-switched Er:YAG laser ablation, In our analysis of phase transitions, tissue is viewed as material consisting of cells that reside in and attach to an extracellular matrix (ECM). In matrix-continuous tissues, the ECM consists largely of collagen, with the collagen content being as high as 35% Both cells and ECM contain large amounts of water that is the main chromophore for IR laser irradiation. Phase transitions of the tissue water are, in most cases, the driving force for JR laser ablation. These phase transitions are strongly modified by the ECM, depending on the mechanical strength of this matrix.

PHASE DIAGRAMS
SURFACE VAPORIZATION
NORMAL BOILING
PHASE EXPLOSIONS AND EXPLOSIVE BOILING
MODIFICATION OF PHASE TRANSITIONS BY THE TISSUE MATRIX
VAPOR EXPLOSION AND PHOTOTHERMAL DISSOCIATION OF THE TISSUE MATRIX
ABLATION UNDER STRESS CONFINEMENT
CONCLUSIONS

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.