Kinetic resolution of allylic alcohols via stereoselective acylation catalyzed by lipase PS-30

Peiran Chen,Peng Xiang

doi:10.1016/j.tetlet.2011.08.093

Kinetic resolution of allylic alcohols via stereoselective acylation catalyzed by lipase PS-30

Peiran Chen, Peng Xiang

https://doi.org/10.1016/j.tetlet.2011.08.093

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Journal: Tetrahedron Letters	Publication Date: Aug 23, 2011
Citations: 14

Affiliation: Donghua University, Shanghai Institute of Organic Chemistry

#Kinetic Resolution Of Allylic Alcohols #Lipase PS-30 + Show 8 more

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Abstract

By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic allylic alcohols has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio ( E) reached up to 968. Substituent effect is briefly discussed.

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